Transcription activation is enhanced by multivalent interactions independent of phase separation https://t.co/5T84i6HgZE
@davidsuter_epfl I also share the same feeling (including the possibility that I'm missing something). The @KarstenRippe preprint on the impact of phase separation on transcriptional activation was an eye-opener for me https://t.co/txEeSO5xLg
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @Anders_S_Hansen: I'm late, but enjoyed this comprehensive dissection by @KarstenRippe Multi-valent TF interactions enhance transcript…
I'm late, but enjoyed this comprehensive dissection by @KarstenRippe Multi-valent TF interactions enhance transcription and also produce droplets when overexpressed But is is the multi-valency and not droplet formation that matters for transcription ht
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
Indeed, data suggest that "Transcription activation is enhanced by multivalent interactions independent of liquid-liquid phase separation" whereby multivalent interactions could be driven by sequence-specific crowding of DNA-bound CTCF and adjacent factors
RT @robert_ife: More to the discussion about phase separation and transcriptional activation....
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
Transcription activation is enhanced by multivalent interactions independent of liquid-liquid phase separation https://t.co/YbFINO2A3k #biophysics https://t.co/YJZrKCLp3A
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @ChromatinHaiku: Single cell viewing Condensates and transcription? No enhancement seen... #ChromatinHaiku #LLPS https://t.co/ARRoUN3en…
Is phase separation a cause or a consequence? Here's a difference voice among the ocean of high profile phase separation papers. https://t.co/kfVyQKOJbx
RT @meshorer1: A very interesting and provocative preprint from @KarstenRippe showing that inducing phase separation of transcriptional act…
RT @meshorer1: A very interesting and provocative preprint from @KarstenRippe showing that inducing phase separation of transcriptional act…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
A very interesting and provocative preprint from @KarstenRippe showing that inducing phase separation of transcriptional activators does not necessarily result in increased transcription. The plot thickens. https://t.co/uFRqUv1F4i
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
Has anyone heard from Rick yet ?
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @hitenmadhani: If I understand it correctly, the work proposes that transcription factor condensates are a functionally irrelevant epiph…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @ChromatinHaiku: Single cell viewing Condensates and transcription? No enhancement seen... #ChromatinHaiku #LLPS https://t.co/ARRoUN3en…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @ChromatinHaiku: Single cell viewing Condensates and transcription? No enhancement seen... #ChromatinHaiku #LLPS https://t.co/ARRoUN3en…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
Wow. This experimental design is so.... tasty...
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @ChromatinHaiku: Single cell viewing Condensates and transcription? No enhancement seen... #ChromatinHaiku #LLPS https://t.co/ARRoUN3en…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @AlexeySoshnev: I felt a great disturbance in the Force, as if millions of voices suddenly cried out in terror... 😜
If I understand it correctly, the work proposes that transcription factor condensates are a functionally irrelevant epiphenomenon produced by their multivalent interactions. The underlying assumption seems to be that natural and induced condensates are f
Careful work as usual from the Rippe lab.
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
And then comes this story...!! No evidence of correlation between transcriptional condensate and increased gene expression
RT @ChromatinHaiku: Single cell viewing Condensates and transcription? No enhancement seen... #ChromatinHaiku #LLPS https://t.co/ARRoUN3en…
Transcription activation is enhanced by multivalent interactions independent of liquid-liquid phase separation https://t.co/iAMS7LT3hH
Top #tweeted story in #structbio: Transcription activation is enhanced by multivalent interactions independent of liquid-liquid phase separation | bioRxiv https://t.co/IDaNsLSRPv, see more https://t.co/ThsI8L7UXY
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
RT @Pha_Tran_Papers: Transcription activation is enhanced by multivalent interactions independent of liquid-liquid phase separation https:/…
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…
Given the amount of attention phase separation in the realm of transcriptional regulation has been getting, this'll be fascinating to see play out as it gets reviewed
RT @KarstenRippe: We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcript…