RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @GWAS_lit: Hidden 'risk' in polygenic scores: clinical use today could exacerbate health disparities https://t.co/mwRxs1P3Gx https://t.c…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @GWAS_lit: Hidden 'risk' in polygenic scores: clinical use today could exacerbate health disparities https://t.co/mwRxs1P3Gx https://t.c…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
The biobank papers are coming. https://t.co/cHYH1W5PMY
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
"Empirically, polygenic risk scores perform far better in European populations, with prediction accuracy reduced by approximately 2- to 5-fold in East Asian and African descent populations, respectively." https://t.co/Rzw2kYDmVp
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
RT @genetisaur: Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk sc…
Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk score accuracy across global population in UK Biobank, we assess prediction accuracy for five diseases here + Biobank Japan, and text r
RT @GWAS_lit: Hidden 'risk' in polygenic scores: clinical use today could exacerbate health disparities https://t.co/mwRxs1P3Gx https://t.c…
RT @GWAS_lit: Hidden 'risk' in polygenic scores: clinical use today could exacerbate health disparities https://t.co/mwRxs1P3Gx https://t.c…
RT @GWAS_lit: Hidden 'risk' in polygenic scores: clinical use today could exacerbate health disparities https://t.co/mwRxs1P3Gx https://t.c…
RT @GWAS_lit: Hidden 'risk' in polygenic scores: clinical use today could exacerbate health disparities https://t.co/mwRxs1P3Gx https://t.c…
RT @GWAS_lit: Hidden 'risk' in polygenic scores: clinical use today could exacerbate health disparities https://t.co/mwRxs1P3Gx https://t.c…
Yet another interesting paper from @genetisaur
RT @GWAS_lit: Hidden 'risk' in polygenic scores: clinical use today could exacerbate health disparities https://t.co/mwRxs1P3Gx https://t.c…
RT @MuinJKhoury: Why the use of polygenic risk scores in clinical practice can exacerbate health disparities. Via @biorxiv_genetic https:/…
RT @GWAS_lit: Hidden 'risk' in polygenic scores: clinical use today could exacerbate health disparities https://t.co/mwRxs1P3Gx https://t.c…
Hidden 'risk' in polygenic scores: clinical use today could exacerbate health disparities https://t.co/mwRxs1P3Gx https://t.co/Nrla2sBfbb
RT @genetisaur: I'm excited to share this perspective with @dalygene, @bmneale, @masakanai, and RIKEN colleagues on the high potential for…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: I'm excited to share this perspective with @dalygene, @bmneale, @masakanai, and RIKEN colleagues on the high potential for…
RT @GENES_PK: For those who couldn't see this in person, the preprint from @genetisaur et al: "Hidden 'risk' in polygenic scores: clinical…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
Mostly pale, male, stale, caucasian Europeans....
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @DrRitaHamad: This is really disturbing. 80% of #GWAS are of Europeans, and that number may be *rising*. It's particularly bad because o…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @GENES_PK: For those who couldn't see this in person, the preprint from @genetisaur et al: "Hidden 'risk' in polygenic scores: clinical…
We need to fix this, this is creating inequality of care, especially once PRS will hit the clinic
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
This is really disturbing. 80% of #GWAS are of Europeans, and that number may be *rising*. It's particularly bad because of the inability to see how social and environmental factors interact with genes, when samples are so homogeneous. @atulbutte @cdbustam
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @GENES_PK: For those who couldn't see this in person, the preprint from @genetisaur et al: "Hidden 'risk' in polygenic scores: clinical…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
RT @bryan_howie: Wow, a really sobering update on our progress (or lack thereof) in diversifying GWAS... https://t.co/jNmADOyKZd
Wow, a really sobering update on our progress (or lack thereof) in diversifying GWAS...
RT @genetisaur: @codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catal…
@codushlaine @dgmacarthur @broadinstitute While this is a common mindset, our work shows otherwise. Based on the GWAS catalog, diversifying progress is stalled, and we are not on a trajectory to level this vast imbalance (https://t.co/4Ws6k0tfNW). https://
RT @genetisaur: I'm excited to share this perspective with @dalygene, @bmneale, @masakanai, and RIKEN colleagues on the high potential for…
RT @GENES_PK: For those who couldn't see this in person, the preprint from @genetisaur et al: "Hidden 'risk' in polygenic scores: clinical…
RT @GENES_PK: For those who couldn't see this in person, the preprint from @genetisaur et al: "Hidden 'risk' in polygenic scores: clinical…
RT @GENES_PK: For those who couldn't see this in person, the preprint from @genetisaur et al: "Hidden 'risk' in polygenic scores: clinical…
#European bias in #genetics studies - Hidden 'risk' in #polygenic scores: #clinical use today could exacerbate health disparities https://t.co/qqTvLxHqgM HT @genetisaur @dgmacarthur #GWAS #Diversity #genomics #science https://t.co/NwM3If5odk
Polygenic risk scores have significantly greater predictive value for individuals of European descent, exacerbating racial health disparities. https://t.co/uMKBGVV9BU
RT @GENES_PK: For those who couldn't see this in person, the preprint from @genetisaur et al: "Hidden 'risk' in polygenic scores: clinical…
RT @GENES_PK: For those who couldn't see this in person, the preprint from @genetisaur et al: "Hidden 'risk' in polygenic scores: clinical…
RT @GENES_PK: For those who couldn't see this in person, the preprint from @genetisaur et al: "Hidden 'risk' in polygenic scores: clinical…
For those who couldn't see this in person, the preprint from @genetisaur et al: "Hidden 'risk' in polygenic scores: clinical use today could exacerbate health disparities" https://t.co/H46fwqbIkx
cool! mark
A recent report form Mark Daly’s group has determined that continuing to use largely European cohorts for genetics studies will likely exacerbate current health disparities. Source: https://t.co/AyixkLdXyN
RT @genetisaur: I'm excited to share this perspective with @dalygene, @bmneale, @masakanai, and RIKEN colleagues on the high potential for…
RT @dalygene: Outstanding work by @genetisaur (and @masakanai) on a very important and (we felt) not sufficiently discussed element of the…
@genetix22 Another call for diverse samples in the genomics community. Spotted plots from recent pre-print concerning bias due to Euro-centric GWAS bias. https://t.co/B727IgWtWh
RT @artwuster: Final talk in Polygenic Risk Score bias session is by @genetisaur. Her paper on the challenges of PRS: https://t.co/mEgPM8yh…
RT @artwuster: Final talk in Polygenic Risk Score bias session is by @genetisaur. Her paper on the challenges of PRS: https://t.co/mEgPM8yh…
RT @artwuster: Final talk in Polygenic Risk Score bias session is by @genetisaur. Her paper on the challenges of PRS: https://t.co/mEgPM8yh…
Final talk in Polygenic Risk Score bias session is by @genetisaur. Her paper on the challenges of PRS: https://t.co/mEgPM8yhN1 #ASHG18
RT @markmccarthyoxf: Looking forward to reading this in detail. Optimistic in terms of solving the challenge of enabling prs usage across m…
RT @genetisaur: I'm excited to share this perspective with @dalygene, @bmneale, @masakanai, and RIKEN colleagues on the high potential for…