RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
i wonder how robust are the GREML assumptions with respect to rare variants…? just asking… 🤔 Recovery of trait heritability from whole genome sequence data https://t.co/iicLTlKcBj
RT @GWAS_lit: Recovery of trait heritability from whole genome sequence data https://t.co/8yYNUswOfp https://t.co/COieU36YXM
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
Surprise! or should I say "Surprise?" https://t.co/zSLabss00c
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
The missing heritability finally found? And yes, it was in in the rare variants.
RT @GWAS_lit: Recovery of trait heritability from whole genome sequence data https://t.co/8yYNUswOfp https://t.co/COieU36YXM
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @philippefroguel: Very important result from Vissher: missing heritability largely explained by rare variants for height and BMI https:/…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
Wow!
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @SteveStuWill: Why are DNA-based heritability estimates lower than those based on twin studies? A big part of it seems to be that the fo…
RT @akousathanas: The culmination of 10 years of GWAS research! Estimated heritability of height =0.79 with whole genome sequence data. "Mi…
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @GWAS_lit: Recovery of trait heritability from whole genome sequence data https://t.co/8yYNUswOfp https://t.co/COieU36YXM
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @akousathanas: The culmination of 10 years of GWAS research! Estimated heritability of height =0.79 with whole genome sequence data. "Mi…
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @SteveStuWill: Why are DNA-based heritability estimates lower than those based on twin studies? A big part of it seems to be that the fo…
Why are DNA-based heritability estimates lower than those based on twin studies? A big part of it seems to be that the former don't take into account rare variants. Doing so gives estimates very close to twin studies. https://t.co/55LNfIZop2 Adios, missing
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @RyanLCollins13: Whoa😮 seems like a pretty major finding: "...variants in the MAF range of 0.0001 to 0.1 explained 0.54 and 0.51 of heri…
This is a big deal. Rare variants account for ~50% heritability of height
RT @GWAS_lit: Recovery of trait heritability from whole genome sequence data https://t.co/8yYNUswOfp https://t.co/COieU36YXM
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @akousathanas: The culmination of 10 years of GWAS research! Estimated heritability of height =0.79 with whole genome sequence data. "Mi…
RT @josep_mercader: Rare variants contribute to the missing heritability of complex traits https://t.co/8BCQYPG9Xd
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @GWAS_lit: Recovery of trait heritability from whole genome sequence data https://t.co/8yYNUswOfp https://t.co/COieU36YXM
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @psychgenomics: Now this is interesting: Use of WGS and GREML establishes they can discover near full twin heritability. "Recovery of tr…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
"variants in the MAF range of 0.0001 to 0.1 explained 0.54 (SE 0.05) and 0.51 (SE 0.11) of heritability for height and BMI, respectively. Our results imply that the still missing heritability of complex traits and disease is accounted for by rare variants"
RT @RyanLCollins13: Whoa😮 seems like a pretty major finding: "...variants in the MAF range of 0.0001 to 0.1 explained 0.54 and 0.51 of heri…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @philippefroguel: Very important result from Vissher: missing heritability largely explained by rare variants for height and BMI https:/…
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
They found the missing heritability everyone go home
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @philippefroguel: Very important result from Vissher: missing heritability largely explained by rare variants for height and BMI https:/…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
Interesting indeed: The remaining unaccounted for missing heritability of height and BMI almost entirely explained by rare variants, based on this analysis of WGS data from over 20k individuals: https://t.co/dVlAlkyARl
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
Rare variants contribute to the missing heritability of complex traits
RT @WiringTheBrain: Recovery of trait heritability from whole genome sequence data https://t.co/T4vswL4luI - really nice papr from @jyang19…
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @casey6r0wn: RIP missing heritability? https://t.co/TnhH8A6KSw
RT @philippefroguel: Very important result from Vissher: missing heritability largely explained by rare variants for height and BMI https:/…
RT @philippefroguel: Very important result from Vissher: missing heritability largely explained by rare variants for height and BMI https:/…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @casey6r0wn: RIP missing heritability? https://t.co/TnhH8A6KSw
RT @GWAS_lit: Recovery of trait heritability from whole genome sequence data https://t.co/8yYNUswOfp https://t.co/COieU36YXM
Recovery of trait heritability from whole genome sequence data https://t.co/aGnNaO0pKa
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @casey6r0wn: RIP missing heritability? https://t.co/TnhH8A6KSw
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
This could be an important paper & ?highlight how informative whole genomes from large cohorts of (rrobustly phenotyped) pts w #IBD will be. Excited to hear the thoughts of @anderson_carl @lukejostins & @jcbarret Meantime at UKIBDGC we're busy seq
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @casey6r0wn: RIP missing heritability? https://t.co/TnhH8A6KSw
"Cumulatively variants in the MAF range of 0.0001 to 0.1 explained 0.54 (SE 0.05) and 0.51 (SE 0.11) of heritability for height and BMI, respectively." If this result generalizes, I guess it will settle the issue.
RT @GWAS_lit: Recovery of trait heritability from whole genome sequence data https://t.co/8yYNUswOfp https://t.co/COieU36YXM
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @RyanLCollins13: Whoa😮 seems like a pretty major finding: "...variants in the MAF range of 0.0001 to 0.1 explained 0.54 and 0.51 of heri…
Wow!! WGS finds the missing heritability; Its in rare variants with low LD.
Visscher and colleagues fire their opening salvo in the bid to eradicate the missing heritability using TOPMed whole genomes. H/t to @casey6r0wn for the find.
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @psychgenomics: Now this is interesting: Use of WGS and GREML establishes they can discover near full twin heritability. "Recovery of tr…
RT @arundurvasula: This is just to say I have found the heritability that was missing in the genome and which you were probably writing…
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic
RT @biorxiv_genetic: Recovery of trait heritability from whole genome sequence data https://t.co/wxb61gjxQn #biorxiv_genetic